[, Murakami K, Ide T, Suzuki M, Mochizuki T, Kadowaki T: Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. Stearic Acid, CAS# 57-11-4, is a saturated fatty acid with an 18-carbon chain manufactured through hydrolysis of triglycerides, available as WHITE FLAKE or white powder. The salts and esters of stearic acid are called stearates. 291570. 204 스테아르산(영어: stearic acid)은 18개의 탄소로 구성된 포화 지방산이고, IUPAC 이름은 옥타데칸산(영어: octadecanoic acid)이다.왁스 같은 고체이고, 화학식은 C18H 36 CO 2 H이다. Type. Brushless shaving creams often have unsaponfied stearic acid to give the cream a smooth, creamy consistency ideal for shaving. Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. 12-Hydroxyoctadecanoic acid … Sigma-Aldrich Products are sold exclusively through Sigma-Aldrich, Inc. Stearic acid 9 Products Synonym: 1- Heptadecanecarboxylic acid, C18:0, Cetylacetic acid, NSC 25956, NSC 261168, Octadecanoic acid, Stearophanic acid This means that the hydrocarbon chain is flexible and can roll up into a ball or stetch out into a long zig-zag. It is made by extraction from tallow, which is the mixture of fats that are obtained by steam treating cow fat. © 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. Accession Number. (Select up to %1% total). The absence of an interaction does not necessarily mean no interactions exist. [, Spector AA, John K, Fletcher JE: Binding of long-chain fatty acids to bovine serum albumin. S Stearic acid plays an important role as an emulsifier in the cosmetic industry. With 12 carbon atoms, lauric acid is the longest of the medium-chain fatty acids. (1-~13~C)Octadecanoic acid. Nat Rev Drug Discov. Arnold W. Fogel, "12-hydroxy stearic acid esters, compositions based upon same and methods of using and making such compositions." Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. Drug created on June 13, 2005 13:24 / Updated on February 21, 2021 18:51, Accelerate your drug discovery research with our fully connected ADMET dataset, With our commercial data, access important information on, Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects, Reduce medical errors & improve treatment outcomes with our adverse effects data. Its name comes from the Greek word στέαρ "stéar", which means tallow. Questions? EC Number 220-336-3. Fattyacids,c16-18. Graph needs axis labels with units, proper scale, data points, title, figure title underneath Conclusion: In this investigation, the melting point of stearic acid was determined by heating solid stearic acid in a water bath using a Bunsen burner. 3.1. Improving the efficacy and texture of cleansers, lotions and skin care/hair products, including sh… Probably involved in lipid transport. | Privacy. Sorry we cannot compare more than 4 products at a time. However, fats and oils rich in stearic acid are more abundant in animal fat (up to 30%) than in vegetable fat (typically less than 5%). It appears as a waxy, yellow-white, solid substance. MDL number MFCD00044082. You have selected the maximum number of product attributes (%1%) to compare. J Lipid Res. Stearic acid (SA), sometimes also called octadecanoic acid, is a saturated long-chain fatty acid. It is also essential ingredient in manufacturing of Potassium Stearate, Sodium … 2006 Oct;5(10):821-34. It’s present in humans, animals and some plants. The important exceptions are cocoa butter and shea butter, where the stearic acid content (as a triglyceride) is 28 to 45%.Stearic acid is obtained from fats and oils by the saponification of the triglycerides using hot water (about 100 °C). Octadecanoic acid-1-13C. Figure 5 shows the results of the titrations of the various C18 fatty acids with hydrochloric acid. Volatilization from moist soil is not expected because the acid exists as an anion and anions do not volatilize(SRC). Stearic acid, United States Pharmacopeia (USP) Reference Standard. Stearic acid, also called Octadecanoic Acid, one of the most common long-chain fatty acids, found in combined form in natural animal and vegetable fats. Spink estimated the pKa of stearic acid monolayers at pH 5.1 in 0.01 M NaCl, also using a Langmuir trough. Stearic acid is a saturated acid, since there are no double bonds between neighbouring carbon atoms. Many animals cannot synthesize linoleic acid (an omega-6 fatty acid) and alpha-linolenic acid (an omega-3 fatty acid). It is a waxy solid. David As its ester, stearic acid is one of the most common saturated fatty acids found in nature following palmitic acid. Stearic acid is a saturated fatty acid found in high quantity in animal fat. It is named after the binomial name for nutmeg (Myristica fragrans), from which it was first isolated in 1841 by Lyon Playfair.. Stearic acid (18:0) is the main fatty acid in the mycelial oil (up to 40%) produced by these mutants (Jareonkitmongkol et al., 2002). Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Gene Name APOM Uniprot ID O95445 Uniprot Name Apolipoprotein M Molecular Weight 21253.105 Da Stearic acid–chitosan complexes demonstrated about eightfold higher transfection efficiency as compared to underivatized chitosan polyplexes. [, Fournier NC, Rahim M: Control of energy production in the heart: a new function for fatty acid binding protein. The pKa of 12-hydroxyoctadecanoic acid is 4.75(3), indicating that this compound will almost entirely exist in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Biochemistry. [, Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Stearic acid. As its name indicates, it is a major component of the oil from the fruit of oil palms ().Palmitic acid can also be found in meats, cheeses, butter, and other dairy products. Stearic Acid is widely used as lubricants, softening and release agents in food production with E number E570. Stearic acid (Octadecanoic acid, Isostearic acid, Cetylacetic acid) is a natural saturated fatty acid found in animal and vegetable fats. Stearic acid, certified reference material. 1985 Apr 23;24(9):2387-96. doi: 10.1021/bi00330a039. Fatty acids C16-18 It could be used as a food additive and used in soaps, cosmetics and detergents. The p Ka values of the fatty acids have been found to increase with the alcohol content of the solvent. Particles in solids have a repeating arrangement with strong intermolecular bonds holding them together (Ryan 11). Biochem Biophys Res Commun. I It is also found in cottonseed oil, pumpkin seed oil, grape seed oil and also in pomegranate seeds. The p Ka values of lauric acid, myristic acid, palmitic acid and stearic acid in methanol‐water and ethanol‐water mixtures of different compositions at 303 K and ionic strength, I =0.1M (KNO 3) have been determined. Please remove at least one to add a new selection. Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms. Contact This information should not be interpreted without the help of a healthcare provider. Making soap and cleansers (one of the most common ways it’s used worldwide) 2. Incubation of subconfluent cultures of the hepatocytes with 250 μmol/l stearic acid for 16 h produced a significant loss of cell viability as demonstrated by decreased reduction of MTT and increased LDH release (Figure (Figure1A). These shaving creams are very much like old style facial creams in the 1920s, 30s and 40s. Squaric acid, also called quadratic acid because its four carbon atoms approximately form a square, is a dibasic organic acid with the chemical formula C 4 O 2 (OH) 2.. Stearic Acid, Pharmaceutical Secondary Standard; Certified Reference Material. Description. Palmitic Acid is a saturated long-chain fatty acid with a 16-carbon backbone.Palmitic acid is found naturally in palm oil and palm kernel oil, as well as in butter, cheese, milk and meat. IDENTIFICATION: Stearic acid is a colorless, waxy solid or white-to yellow powder or crystals. The conjugate base of squaric acid is the hydrogensquarate anion C 4 HO − 4; and the conjugate base of the hydrogensquarate anion is the divalent squarate anion C 4 O 2− 4.This is one of the oxocarbon …
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